in which Z denotes an oxygen atom, R4 denotes a hydrogen atom, a chlorine atom, R6 and/or R7 can have an α or β configuration, and R6 and R7 independently denote a hydrogen atom or straight or branched alkyl group containing 1-4 or 3-4 carbon atoms, or a straight or branched alkenyl group containing 2-4 or 3-4 carbon atoms, or a saturated cycloalkyl group containing 3-5 carbon atoms, or together denote a methylene group or a double bond.;EFFECT: novel compounds have progestational activity and antimineralocorticoid activity.;2 cl, 20 ex"/>
18-METHYL-19-NORANDROST-4-ENE-17,17-SPIROETHER (18-METHYL-19-NOR-20-SPIROX-4-EN-3-ON) AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUND
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18-METHYL-19-NORANDROST-4-ENE-17,17-SPIROETHER (18-METHYL-19-NOR-20-SPIROX-4-EN-3-ON) AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUND
18-METHYL-19-NORANDROST-4-ENE-17,17-SPIROETHER (18-METHYL-19-NOR-20-SPIROX-4-EN-3-ON) AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUND
FIELD: chemistry.;SUBSTANCE: invention describes novel 18-methyl-19-norandrost-4-ene 17,17-spiroethers of general formula 1 in which Z denotes an oxygen atom, R4 denotes a hydrogen atom, a chlorine atom, R6 and/or R7 can have an α or β configuration, and R6 and R7 independently denote a hydrogen atom or straight or branched alkyl group containing 1-4 or 3-4 carbon atoms, or a straight or branched alkenyl group containing 2-4 or 3-4 carbon atoms, or a saturated cycloalkyl group containing 3-5 carbon atoms, or together denote a methylene group or a double bond.;EFFECT: novel compounds have progestational activity and antimineralocorticoid activity.;2 cl, 20 ex
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