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METHOD FOR PREPARING NON-TOXIC POROUS IMPLANT OF POLYLACTIC ACID FOR BUILDING OF LONG BONE DEFECTS

机译:长形骨缺损的聚乳酸无毒多孔接枝的制备方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, particularly traumatology and orthopedics, and can find application in treating false joints of long bones. What is described is a method for preparing a non-toxic porous implant of polylactic acid with controlled pore size for building of long bone defects involving melting the polylactic acid granules in a melting pot immersed in thermally stable oil with porogen presented by sodium chloride crystals 100-250 nm to be washed out by aqueous solutions of antiseptics. The implant is prepared with no toxic solvents added and has a pre-set pore diameter.;EFFECT: improved efficiency of the method.
机译:领域:药物;发明:本发明涉及药物,尤其是创伤学和骨科,并且可以发现其在治疗长骨假关节中的应用。所描述的是一种制备具有受控孔径的聚乳酸无毒多孔植入物的方法,该植入物用于构建长骨缺损,该方法包括在浸入热稳定油中的融化锅中融化聚乳酸颗粒,该成孔剂由氯化钠晶体制成,具有成孔剂100 -250 nm要用防腐剂水溶液冲洗掉。植入物是在不添加有毒溶剂的情况下制备的,并且具有预设的孔径。效果:提高了该方法的效率。

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