DISSOCIATING IN ORAL CAVITY PROGESTIN-CONTAINING SOLID DOSED FORMS, AND METHODS OF OBTAINING AND APPLICATION OF SAID DOSED FORMS

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: non-sparkling dissociating in oral cavity pharmaceutical solid dosed form contains progestin in quantity, equivalent to from 0.5 to 2 mg of levonorgestrel, ionic disintegrant in quantity from 8% to 60% of dosed form weight and hydrophilic water-insoluble in nonionic filler in quantity from 1% to 20% of dosed form weight. Also described is therapeutic set, which includes dosed form, and methods of its application. Solid dosed from by invention is characterised by fast dissociation in oral cavity, does not require washing down by water, ensures effective absorption (suction) and high of progestin bio-availability.;EFFECT: pharmaceutical dosed form by invention is suitable for treatment of women, requiring urgent contraception.;29 cl, 10 dwg, 23 tbl, 8 ex;.