MICRORNA THAT REGULATES MUSCLE CELL PROLIFERATION AND DIFFERENTIATION

摘要

PROBLEM TO BE SOLVED: To provide methods and compositions for modulating gene expression in a myocyte.SOLUTION: There are provided a pharmaceutical composition for the treatment of a muscle injury in a patient consisting of an effective amount of miR-206 or a vector encoding miR-206, and a method for increasing myocyte differentiation or inhibiting myocyte proliferation. The method comprises bringing precursor cells of adult skeletal muscle into contact with miR-206 or a vector encoding miR-206 in vitro.