METHOD FOR DETECTING GENETIC ABNORMALITY IN NEUROBLASTOMA USING BLOOD-DERIVED SPECIMEN

摘要

PROBLEM TO BE SOLVED: To provide a noninvasive method for detecting a neuroblastoma without extracting tumor tissue.SOLUTION: The method is provided for detecting LOH (loss of heterozygosity) on chromosome 11 by performing PCR with a microsatellite sequence as a target in a blood-derived specimen, and methods are provided for detecting the neuroblastoma by detecting the LOH, and predicting a prognosis.