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CELL CULTURE SUBSTRATE, METHOD FOR CELL CULTURE USING THE SAME, AND METHOD FOR DIFFERENTIAL INDUCTION OF MULTIPOTENT STEM CELL

机译:细胞培养基质,使用其的细胞培养方法以及用于多能干细胞的差异诱导方法

摘要

PROBLEM TO BE SOLVED: To provide a cell culture substrate that can differentiate multipotent stem cells into cardiomyocytes without needing IGFBP of high concentration, and a method for cell culture using the cell culture substrate, and a method for differential induction of multipotent stem cells.SOLUTION: A cell culture substrate is characterized in that polypeptide comprising the whole or partial region of protein that belongs to an insulin-like growth factor binding protein (IGFBP) family, or fusion protein containing the whole or part of the protein belonging to the insulin-like growth factor binding protein family is fixed or coated onto the surface.
机译:解决的问题:提供一种无需高浓度IGFBP就可将多能干细胞分化为心肌细胞的细胞培养底物,以及使用该细胞培养底物进行细胞培养的方法以及用于多能干细胞的差异诱导的方法。 :细胞培养底物的特征在于,多肽包含属于胰岛素样生长因子结合蛋白(IGFBP)家族的蛋白质的全部或部分区域,或包含属于胰岛素的蛋白质的全部或部分蛋白质的融合蛋白如生长因子结合蛋白家族被固定或包被在表面上。

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