Asymmetric addition reaction, a chiral ligand which is specifically used for the transition metal catalyst in the hydrogenation

摘要

In the form of a mixture of diastereomers or pure diastereomers, formula _(I): (I) wherein, secondary phosphine substituents (= O) HR 1 secondary phosphine -Q-P be a secondary phosphine group having a hetero-hydrocarbon group or a hydrocarbon group as; two phosphorus atoms are bonded to the ortho position relative to the cross-linked heteroaryl or bis bis-aryl, Q is, axially chiral centers or a heteroaryl group or a bis bivalent bisaryl having, or is Q, phosphate atom of the secondary phosphine is bonded via a C ₁ ~C ₄ or carbon bond directly to the cyclopentadienyl ring, a bivalent ferrocenyl group having no surface chiral centers or having a surface chiral centers, _one group -P * ^{(= O)} HR is the secondary phosphine which is attached thereto at the same cyclopentadienyl ring is bound to the cyclopentadienyl ring or otherwise bonded to the ortho position with respect to; hydrocarbon group, P ^* is, R _1, and the phosphorus atom chiral ferrocenyl group or hetero-hydrocarbon radical is, when it is bivalent ferrocenyl radical Q is no chiral center plane, R ₁ is a ligand represented by the formula is a ferrocenyl group having a chiral center plane here. Asymmetric addition reaction, metal complexes of these ligands are homogeneous hydrogenation catalyst in particular.