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MICRO FLOW CHANNEL, MICROCHIP, COLUMN AND DEVICE FOR NUCLEIC ACID HYBRIDIZATION AND NUCLEIC ACID HYBRIDIZATION METHOD
MICRO FLOW CHANNEL, MICROCHIP, COLUMN AND DEVICE FOR NUCLEIC ACID HYBRIDIZATION AND NUCLEIC ACID HYBRIDIZATION METHOD
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机译:核酸加氢的微流路,微芯片,柱和装置及核酸加氢方法
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摘要
PROBLEM TO BE SOLVED: To provide a method and device that can easily carry out high sensitive detection of hnRNP-B1 gene mRNA which is expected to be applied as a diagnosis marker for early stage lung cancer.;SOLUTION: There is provided a micro flow channel 11 for nucleic acid hybridization through which a sample liquid including hnRNP-B1 gene mRNA flows, and in which an agarose gel carrier 2 (agarose gel bead) in which a capturing chain having a specific base sequence complementary to hnRNP-B1 gene mRNA is solidified is filled while being retained therein by a filter 113 disposed downstream of the channel in the sample liquid delivery direction.;COPYRIGHT: (C)2013,JPO&INPIT
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机译:解决的问题:提供一种可以容易地对hnRNP-B1基因mRNA进行高灵敏度检测的方法和装置,该方法和装置有望用作早期肺癌的诊断标志物。核酸杂交通道11,其中包含hnRNP-B1基因mRNA的样品液体流过该通道,并且其中带有具有与hnRNP-B1基因mRNA互补的特定碱基序列的捕获链的琼脂糖凝胶载体2(agarose gel bead)在其中流动凝固的固体在被留在样本液体输送方向上位于通道下游的过滤器113填充的同时被填充。版权所有:(C)2013,JPO&INPIT
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