SURFACE MODIFICATION MATERIAL FOR IMMOBILIZING PROTEIN

摘要

PROBLEM TO BE SOLVED: To provide a new compound which is a silane compound, with which a hydroxysuccinimido ester group for immobilizing protein is introduced onto a substrate surface with one step, and which yields a modification material capable of building a high density monomolecular film applicable to a highly sensitive sensing element substrate for a biosensor.;SOLUTION: The hydroxysuccinimido ester-silane compound is represented by chemical formula (1) (wherein each of X₁ to X₃ independently represents a halogen, a 1-3C alkoxy group, or a 1-3C alkyl group, R₁ represents a 1-10C straight alkyl chain, and R₂ represents -(CH₂)_m-(OCH₂CH₂)_n- or -(CH₂CH₂O)_n-(CH₂)_m-; m is an integer of 3-30, n is an integer of 0-20, and m+n≥3).;COPYRIGHT: (C)2013,JPO&INPIT