N- (heteroaryl) -1H-indole-2-carboxamide derivatives and their use as vanilloid TRPV1 receptor ligands

摘要

The invention concerns therapeutic uses of compounds of general formula (I), wherein n, X1, X2, X3, X4, Z1, Z2, Z3, Z4, Z5 and W are as defined herein. Said compounds are ligands of the TRPV1 vanilloid receptor, and are therefore, useful for treating diseases associated with TRPV1 receptors, such as pain and inflammation among others as disclosed and specifically claimed.