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Generation of specific CTL lines against multiple tumor antigens or viruses cross-reference of related applications
Generation of specific CTL lines against multiple tumor antigens or viruses cross-reference of related applications
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机译:针对多种肿瘤抗原或病毒的特异性CTL系的产生[相关应用的交叉引用]
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摘要
The present invention encompasses methods and compositions for the generation and use of cytotoxic T lymphocytes that target multiple viruses or that are specific for multiple tumor antigens. In specific embodiments, the generation methods employ use of certain cytokines to promote proliferation and reduce cell death in an activated T cell population and/or that employ a particular bioreactor having a gas permeable membrane.
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