Carbon to transition metal-catalyzed - nitrogen bond and carbon-carbon bond forming reactions

摘要

Viewed from one aspect, the invention relates to ligands for transition metals. When viewed from the side of the second, carbon as a catalyst a variety of transition metal present invention, - carbon and heteroatom bond - in the carbon bond-forming reaction relates to the use of a catalyst comprising these ligands. By this method, improvement was brought about, including the reaction efficiency range of a suitable substrate, the rotational speed of the catalyst, and the reaction conditions, the number of features of the reaction catalyzed by transition metal. For example, improvements have been identified in and Sonogashira coupling aryl amination reactions catalyzed by transition metals, aryl amidation reaction, and Suzuki coupling, in certain embodiments, the present invention is a catalyst in an aqueous solvent system and relates to the implementation of the method using the same.