Are not processed and a system for measuring the type A neurotoxin which is partially processed

摘要

The present invention relates to a tool for safety and quality control in the manufacturing process of the neurotoxin. Of solution containing BoNT / A that are not processed BoNT / A and / or is partially processed and (BoNT / A) botulinum neurotoxin A processed polypeptide, the invention is partially processed, particularly The method of measuring the amount of BoNT / A that are not processed BoNT / A and / or, specifically with the BoNT / A that are not processed and BoNT / A has been partially processed, a sample of the solution the step of contacting under conditions which allow the capture antibody that binds to the binding of a BoNT / A that are not processed and BoNT / A has been processed the partially antibody, the complex is formed thereby and, a step of measuring the amount of complex formed, indicating the amount of BoNT / A that are not processed BoNT / A and / or amount of the complex is partially processed in the solution thus on how to include the. The present invention relates to devices and kits for carrying out the above method. None [Selection Figure]