Production method of homoallylic hydrazide, asymmetric catalyst and is used to it

摘要

PROBLEM TO BE SOLVED: To provide a method for producing a homoallyl hydrazide by allylating N-acylhydrazone by using monovalent indium, and to provide an asymmetric catalyst for use therein.;SOLUTION: The method for producing the homoallyl hydrazide includes reacting N-acylhydrazone represented by formula I (wherein, R¹ is an aliphatic hydrocarbon group which may have a substituent, an aromatic hydrocarbon group which may have a substituent, or an alkoxycarbonyl group; R² is a hydrogen atom or an alkyl group; and R³ is an aliphatic hydrocarbon group which may have a substituent, or an aromatic hydrocarbon group which may have a substituent) with an α-substituted allylboronate represented by formula II (wherein, R⁴s are the same or different and each an alkyl group; R⁵ is a hydrogen atom, a hydrocarbon group, a halogen group or an alkoxy group; and R⁶ to R⁸ are the same or different and each a hydrogen atom or an alkyl group) in the presence of a monovalent indium salt.;COPYRIGHT: (C)2010,JPO&INPIT