ASYMMETRIC CATALYST PRODUCTION METHOD OF 3-ALLYL-3-AMINO-2-OXINDOLE DERIVATIVE HAVING OPTICAL ACTIVITY FOUR SUBSTITUTED ASYMMETRIC CARBON

摘要

PROBLEM TO BE SOLVED: To solve the problem that there is not a simple and easy and catalyst high enantioselective synthesis method of an optical activity 3-allyl-3-amino-2-oxindole derivative in a present art.;SOLUTION: There is provided a method for producing an optical activity 3-allyl-3-amino-2-oxindole derivative by making trimethoxysilane react with various isatin derived imines represented by the following formula (1) under the presence of a catalyst and a silver salt.;COPYRIGHT: (C)2014,JPO&INPIT