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Treatment of tumor protein 63-related diseases by inhibition of natural antisense transcripts against tumor protein 63 (p63)

机译:通过抑制针对肿瘤蛋白63的天然反义转录本来治疗与肿瘤蛋白63相关的疾病(p63)

摘要

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Tumor Protein 63 (p63), in particular, by targeting natural antisense polynucleotides of Tumor Protein 63 (p63). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of p63.
机译:本发明涉及调节肿瘤蛋白63(p63)的表达和/或功能的反义寡核苷酸,特别是通过靶向肿瘤蛋白63(p63)的天然反义多核苷酸。本发明还涉及这些反义寡核苷酸的鉴定及其在治疗与p63表达有关的疾病和病症中的用途。

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