And use thereof probe for detecting polymorphisms MPL gene

摘要

For MPL gene, it can be determined by a superior reliability and simple polymorphism, is to provide a probe and applications for polymorphism detection. The following (P1), (P1 '), (P2) and (P2' and a probe for detecting polymorphisms of MPL gene, a probe comprising an oligonucleotide of at least one of). (P1) base length is 9-50 bases in length, consists of a nucleotide sequence comprising the nucleotide number 11535-11543 in SEQ ID NO: 1, 3, the base of the base number 11543 'oligonucleotide having a terminal area (P1') (P2) the base length is 10 to 50 bases long oligonucleotide having a nucleotide sequence complementary to the oligonucleotide (P1) above, consists of the nucleotide sequence comprising the nucleotide numbers 11535-11544 of SEQ ID NO: 1, the nucleotide number an oligonucleotide having a nucleotide sequence complementary to the oligonucleotide '(said (P2) P2) oligonucleotide with the 3' end region, the base 11544