OPTIMIZED METHOD FOR OBTAINING ACE ACTIVITY INHIBITORY PEPTIDES FROM WHEY, ACE INHIBITORY PEPTIDES AND FOOD COMPRISING THEM

摘要

An optimized method for obtaining ACE activity inhibitory peptides includes the steps of whey ultrafiltration for obtaining a whey concentrate, enzymatic hydrolysis, hydrolysate ultrafiltration and inhibitory peptide separation. The method includes selecting and adding a mixture having suitable proportion and amount of two microbial proteases and having complementary action to the whey concentrate for the hydrolysis thereof in order to obtain peptides with an ACE inhibition percentage greater than 70% and an IC₅₀ index of 30 to 100 μg/ml.