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Epigallocatechin dimers or trimers having lipase inhibitory activity and/or antioxidant activity

机译:具有脂肪酶抑制活性和/或抗氧化活性的表没食子儿茶素二聚体或三聚体

摘要

An object of the present invention is to provide a lipase activity inhibitor that shows high inhibitory activity against pancreatic lipase to suppress the absorption of meal-derived fat and/or which contributes to suppressing and preventing obesity, as well as a food or beverage that has such lipase activity inhibitor incorporated therein. Another object of the invention is to provide a lipase inhibitor of tea origin that suits most consumers' taste and which will not impair the flavor of the food or beverage when incorporated therein. Still another object of the invention is to provide a process for producing said lipase inhibitors. Further object of the invention is to provide antioxidants. To attain these objects, epigallocatechin dimers (oolong homobisflavans) or trimers are incorporated in foods or beverages. As a result, the absorption of meal-derived fat can be suppressed and, in addition, antioxidation effect is obtained. The compounds of the invention can be produced by reacting epigallocatechin gallate with formaldehyde in the presence of an acid.
机译:本发明的目的是提供一种脂肪酶活性抑制剂,其具有对胰脂肪酶具有高抑制活性以抑制膳食中脂肪的吸收和/或有助于抑制和预防肥胖症,以及提供了一种脂肪酶活性抑制剂。掺入其中的这种脂肪酶活性抑制剂。本发明的另一个目的是提供一种茶来源的脂肪酶抑制剂,其适合大多数消费者的口味并且当掺入其中时不会损害食品或饮料的风味。本发明的另一个目的是提供一种生产所述脂肪酶抑制剂的方法。本发明的另一个目的是提供抗氧化剂。为了达到这些目的,将表没食子儿茶素二聚体(乌龙二黄酮)或三聚体掺入食品或饮料中。结果,可以抑制来自膳食的脂肪的吸收,此外,获得抗氧化作用。本发明的化合物可以通过使表没食子儿茶素没食子酸酯与甲醛在酸存在下反应来制备。

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