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Spores for the stabilization and on-site application of bacterial whole-cell biosensing systems
Spores for the stabilization and on-site application of bacterial whole-cell biosensing systems
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机译:孢子用于细菌全细胞生物传感系统的稳定和现场应用
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摘要
The presently-disclosed subject matter is directed to biosensors comprising spore-forming bacterial cells and/or spores generated therefrom, a recognition unit within each spore-forming cell for binding an analyte of interest, and a reporter molecule within each spore-forming cell for detecting binding of the analyte of interest, wherein the reporter molecule generates a detectable signal upon binding of the analyte by the recognition element. The presently-disclosed subject matter further provides methods of using the biosensors and systems and kits including the biosensors.
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