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intravesical lu00e6gemiddelafgivelsesindretning and approach

机译:膀胱内淋巴结切除术和入路

摘要

Implant devices for intravesical administration and local drug delivery. The device has a body which includes a hollow tube formed of a biocompatible material; at least one reservoir in the tube which contains a drug; and one or more apertures through which the drug can be released. The device is configured for minimally invasive insertion into a body cavity, such as the bladder. The hollow tube may be elastomeric to permit the device to be elastically deformed from its initial shape into an elongated shape for passage through a catheter, where following such passage the device can return to or toward its initial shape to facilitate retention of the device in the body cavity. The body may have a narrow, elongated shape effective to permit insertion of the drug delivery device through a catheter without necessarily deforming the body, yet include flexible projections which effect retention within the body cavity.
机译:用于膀胱内给药和局部药物输送的植入装置。该装置具有主体,该主体包括由生物相容性材料形成的中空管。管中至少有一个装有药物的容器;以及一个或多个可以释放药物的孔。该设备被配置为以微创方式插入体腔,例如膀胱。中空管可以是弹性体,以允许装置从其初始形状弹性变形为细长形状,以通过导管,其中,在这种通过之后,装置可以返回或朝向其初始形状,以利于将装置保持在导管中。体腔。主体可以具有狭窄的细长形状,该形状有效地允许药物输送装置通过导管插入而不必使主体变形,但是还包括影响在体腔内保持的柔性突起。

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