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KAPPA-OPIAT AGONISTS FOR TREATMENT OF DIARY-DOMINANT AND ALTERNATIVE IRRITABLE GAS Syndrome
KAPPA-OPIAT AGONISTS FOR TREATMENT OF DIARY-DOMINANT AND ALTERNATIVE IRRITABLE GAS Syndrome
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机译:KAPPA阿片类药物治疗乳腺和交替性易激性气体综合症
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摘要
The present invention concerns methods useful in treating one or more subtypes of irritable bowel syndrome (IBS), or useful in treating diarrhea. The invention relates to the use of peripherally selective kappa-opiate agonists, especially N-methyl-N-[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidin-1-yl)ethyl]-2,2-diphenylacetamide and/or a pharmaceutically acceptable salt thereof for treating a subject having IBS with alternating diarrhea and constipation (IBS-A).
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