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PRRSV ANTIGENIC SITES IDENTIFYING PEPTIDE SEQUENCES OF PRRS VIRUS FOR USE IN VACCINES OR DIAGNOSTIC ASSAYS
PRRSV ANTIGENIC SITES IDENTIFYING PEPTIDE SEQUENCES OF PRRS VIRUS FOR USE IN VACCINES OR DIAGNOSTIC ASSAYS
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机译:鉴定PRRS病毒肽序列的PRRSV抗原位点,用于疫苗或诊断分析
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摘要
The invention provides antigenic sites of PRRSV isolates. The antigenic sites are neutrahzmg, conserved, non-conserved and conformational, can elicit axntihodiee and are found on protein GP 4 and N encoded by ORF4- and ORF7 of PRRSV. The peptide sequences identified by the sites can be incorporated in vaccines directed against PRRS and in diagnostic tests for PRRS. Also, discriminating tests can be developed that can be used next to marker vaccines in programs designed to eradicate PRRS from pig herds.
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