PRRSV ANTIGENIC SITES IDENTIFYING PEPTIDE SEQUENCES OF PRRS VIRUS FOR USE IN VACCINES OR DIAGNOSTIC ASSAYS

摘要

The invention provides antigenic sites of PRRSV isolates. The antigenic sitesare neutralizing, conserved, non-conserved andconformational, can elicit antibodies and are found on protein GP4 and Nencoded by ORF4 and ORF7 of PRRSV. The peptide sequencesidentified by the sites can be incorporated in vaccines directed against PRRSand in diagnostic tests for PRRS. Also, discriminating testscan be developed that can be used next to marker vaccines in programs designedto eradicate PRRS from pig herds.