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Trna transcription cassette comprising human and non-mammalian trna and vertebrate cell comprising such
Trna transcription cassette comprising human and non-mammalian trna and vertebrate cell comprising such
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机译:包含人和非哺乳动物的trna的Trna转录盒和包含该RNA的脊椎动物细胞
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摘要
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in vertebrate cells. The components include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNA's/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in vertebrate cells are also provided.
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