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PROCESS FOR THE PREPARATION OF 1-METHYL-2-N-4-(N-N-HEXYLOXY CARBONYLAMIDINO) PHENYL AMINO METHYLBENZIMIDAZOL-5-YL-CARBOXYLICACID-N-(2-PYRIDYL)-N-(2-ETHOXYCARBONYLETHYL)AMIDE METHANESULFONATE
PROCESS FOR THE PREPARATION OF 1-METHYL-2-N-4-(N-N-HEXYLOXY CARBONYLAMIDINO) PHENYL AMINO METHYLBENZIMIDAZOL-5-YL-CARBOXYLICACID-N-(2-PYRIDYL)-N-(2-ETHOXYCARBONYLETHYL)AMIDE METHANESULFONATE
The present invention relates to process for the preparation of l-methyl-2-[N-[4-(N-n- hexyloxycarbonylamidino)phenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2- ethoxycarbonylethyl)amide methanesulfonate, represented by the following structural formula-1. Further, the present invention also provides l-methyl-2-[N-[4-amidinophenyl]aminomethyl] benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2- ethoxycarbonylethyl)amide oxalate salt, represented by following structural formula-3a, an useful intermediate in the synthesis of highly pure compound of formula-1.
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