FOLIC ACID CONJUGATED POLYMERIC NANOPARTCLES FOR ORAL DELIVERY OF BIOACTIVE AGENTS

摘要

The invention provides a pharmaceutical nanoformulation for oral delivery of bioactive agents comprising folic acid conjugated to biodegradable polymeric nanoparticles. The said nanoformulation improves bioavailability and enhances efficacy of orally delivered bioactive agents by enhancing intracellular uptake from the gastrointestinal tract (GIT). The invention also provides a process for preparing the folic acid conjugated polymeric nanoparticles.