METHOD AND COMPOSITION FOR TREATING MACULAR DEGENERATION using 15-keto-prostaglandin such as 13,14-dihydro-15-keto-20-ethyl-prostagladin F2-alpha isopropyl ester

摘要

596035 Disclosed herein is the use of a 15-keto prostaglandin compound of formula (I), wherein the variables are defined herein, in the treatment of macular degeneration. Additionally disclosed are pharmaceutical compositions comprising said compound wherein said composition is an ophthalmic composition for ocular topical administration formulated as a sterile unit dose type eye drop containing no preservatives, such as benzalkonium chloride. Specifically exemplified is the use of 13,14-dihydro-15-keto-20-ethyl-PGF2? isopropyl ester(isopropyl unoprostone).