Method for the diagnosis, prognosis and treatment of metastatic breast cancer.

摘要

The present invention relates to a method for diagnosis and / or prognosis of metastasis in ER + breast comprising measuring expression levels of c-MAF gene or protein encoded by said gene in the primary tumor cancer, wherein if the expression levels of said gene are increased their levels of expression in the control sample, then that subject is a positive diagnosis of metastasis or greater propensity to develop metastases. Furthermore, the invention also relates to the use of c-MAF gene and / or c-MAF protein as a therapeutic target for treatment of metastatic breast cancer ER +.