AGO Recommendations for Diagnosis and Treatment of Patients with Primary and Metastatic Breast Cancer. Update 2011

摘要

For the last 10 years, the Breast Committee of the Arbeitsgemeinschaft Gynäkologische Onkologie (German Gynecological Oncology Group, AGO) has been preparing and updating evidence-based recommendations for the diagnosis and treatment of patients with early breast cancer and metastatic breast cancer (MBC). The AGO Breast Committee consists of 44 gynecological oncologists specialized in breast cancer as well as interdisciplinary members specialized in pathology, radiological diagnostics, medical oncology, and radiotherapy. The update is performed according to documented rules by thoroughly reviewing and scoring chapter by chapter the recent publications for its scientific validity (Oxford Level of Evidence; LoE; www.cebm.net[34]) and its clinical relevance (AGO Grades of Recommendation; table ​table1).1). Here, we present the 2011 update of these guidelines focusing on modifications performed for the 2011 version. The full version of the update is available in PDF format online (www.ago-online.de, ‘Leitlinien’) [2] in an English and a German version.