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The dosage regimen for treating a traumatic brain injury progesterone

机译:治疗外伤性黄体酮的剂量方案

摘要

Progesterone for use in treating traumatic brain injury, wherein said progesterone paraadministración is prepared a human subject in at least one cycle of therapy, wherein said cycle of therapy comprises laadministración a regimen intravenous dosing two therapeutically effective levels of progesterone, said dosing regimen two levels comprising a first period of time of at least 1 hour, wherein the subject seadministra high dose infusion progesterone per hour of about 0.1 mg / kg / hr aaproximadamente 7.1 mg / kg / hr, followed by a second period of time when administered to said subject unadosis lower infusion progesterone per hour of about 0.05 mg / kg / hr to about 5 mg / kg / hr.
机译:用于治疗外伤性脑损伤的孕酮,其中所述孕激素副施用在至少一个治疗周期中被制备为人类受试者,其中所述治疗周期包括laadministración静脉内给药两个治疗有效水平的孕酮的方案,所述给药方案两个水平包括至少1小时的第一时间段,其中受试者西达米特高剂量输注黄体酮每小时约0.1mg / kg / hr,氨甲im呤7.1mg / kg / hr,随后是第二段时间,当给予所述受试者无畸形时将孕激素每小时降低约0.05毫克/千克/小时至约5毫克/千克/小时。

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