首页>
外国专利>
Transformed strain derived from a strain deficient in protein and multidrug efflux bioconversion method using the same
Transformed strain derived from a strain deficient in protein and multidrug efflux bioconversion method using the same
展开▼
机译:来自缺乏蛋白质的菌株的转化菌株和使用该菌株的多药外排生物转化方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
Disclosed is a means for improving the poor conversion efficiency in a conventional bioconversion system using a transformant which is given by introducing a gene originated from xerogenic organisms. A transformant is prepared by using a host which is defective in a gene encoding a multidrug efflux protein and introducing a gene originated from xerogenic organisms. Use of the transformant results in much effective microbial conversion of a hydrophobic or amphipathic substrate compound into a desired compound. In case, an Escherichia coli is used as the host, the gene encoding a multidrug efflux protein to be defective may be tolC, acrA, acrB and the like.
展开▼