SUBSTITUTED PYRAZINOYLGUANIDINE COMPOUNDS AND THEIR USE AS EPITHELIAL SODIUM CHANNEL BLOCKERS, MEDICAMENTS CONTAINING SAID COMPOUNDS AND PROCESSES FOR THE PREPARATION THEREOF

摘要

The present invention relates to compounds of general formula (I) and the tautomers and the salts thereof, particularly the pharmaceutically acceptable salts thereof with inorganic or organic acids and bases, which have valuable pharmacological properties, particularly an inhibitory effect on epithelial sodium channels, the use thereof for the treatment of diseases, particularly diseases of the lungs and airways.