SUBSTITUTED PYRAZINOYLGUANIDINE COMPOUNDS AND THEIR USE AS EPITHELIAL SODIUM CHANNEL BLOCKERS, MEDICAMENTS CONTAINING SAID COMPOUNDS AND PROCESSES FOR THE PREPARATION THEREOF

摘要

Le present invention relates to compounds of general formula (I) and thetautomers and the salts thereof, particularlythe pharmaceutically acceptable salts thereof with inorganic or organic acidsand bases, which have valuable pharmacologicalproperties, particularly an inhibitory effect on epithelial sodium channels,the use thereof for the treatment of diseases, particularlydiseases of the lungs and airways.