PPAR-gamma agonists for the induction of cationic antimicrobial peptide expression as immunoprotective stimulants

摘要

Rosiglitazone, 5-ASA or structurally analogous Compounds according to the generalformula (I): or Compounds according to the general formula (Ia): For the inductionof CAMP expression in tissues having PPAR-gamma receptors. Such tissues includeepithelia or mucosae tissue having PPAR-gamma receptors and of particular interestιs CAMP expression in the gut