Cartilage intermediate layer protein 2 C1 and its use to differentiate osteoarthritis from rheumatoid arthritis and non-disease conditions

摘要

The inventions relates method for differentiation of osteoarthritis from rheumatoid arthritis and non-disease conditions in a sample, comprising measuring in the sample the concentration of human cartilage intermediate layer protein 2(CILP-2) in body fluids and more specifically, measuring in the sample the concentration of the N-terminal part of CILP-2 (2Cl) or fragments thereof. The invention also regards antibodies immunoreactive with the protein or fragments thereof and a kit comprising such an antibody and instructions for use in conducting an assay.