首页>
外国专利>
Discovery of regulatory T cells programmed to suppress an immune response
Discovery of regulatory T cells programmed to suppress an immune response
展开▼
机译:发现被调节为抑制免疫反应的调节性T细胞
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method to treat an autoimmune disease is provided. The method involves administration of interleukin-15 receptor (IL-15R) agonists in an amount effective to ameliorate a symptom of the autoimmune disease. The invention also involves a method to treat an autoimmune disease by ex- vivo expansion of CD44+CD122+Kir+ CD8+ Treg cells and administration of the CD44+CD122+Kir+ CD8+ Treg cells. Compositions comprising CD44+CD122+Kir+ CD8+ Treg cells are also provided. Methods for stimulating an immune response to an antigen are also provided.
展开▼
机译:提供了一种治疗自身免疫疾病的方法。该方法包括以有效改善自身免疫疾病症状的量施用白介素-15受体(IL-15R)激动剂。本发明还涉及通过体外扩增CD44 + CD122 + Kir + CD8 + Treg细胞并施用CD44 + CD122 + Kir + CD8 + Treg细胞来治疗自身免疫疾病的方法。还提供了包含CD44 + CD122 + Kir + CD8 + Treg细胞的组合物。还提供了刺激对抗原的免疫应答的方法。
展开▼