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METHOD FOR SCREENING FOR THERAPEUTIC AGENT FOR CARTILAGE DISEASES, AND GENETICALLY MODIFIED CARTILAGE CELL FOR USE IN TREATMENT OF CARTILAGE DISEASES
METHOD FOR SCREENING FOR THERAPEUTIC AGENT FOR CARTILAGE DISEASES, AND GENETICALLY MODIFIED CARTILAGE CELL FOR USE IN TREATMENT OF CARTILAGE DISEASES
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机译:筛选用于软骨疾病的治疗剂以及经遗传修饰的用于治疗软骨疾病的软骨细胞的方法
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摘要
A substance capable of increasing a cartilage mass and/or capable of normalizing the differentiation into cartilage cells can be screened using salt-inducible kinase 3. A genetically modified cartilage cell in which the expression or function of salt-inducible kinase 3 gene is suppressed or enhanced can be used for ameliorating diseases in which the cartilage mass decreases and/or diseases in which the growth of cartilage is impaired.
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