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Screening method for therapeutic agents for cartilage diseases and modified chondrocytes for treating cartilage diseases
Screening method for therapeutic agents for cartilage diseases and modified chondrocytes for treating cartilage diseases
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机译:软骨疾病治疗剂的筛选方法和用于治疗软骨疾病的改良软骨细胞
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摘要
The use of salt-inducible kinase 3 allows screening for a substance having an effect of increasing cartilage volume and/or an effect of normalizing chondrocyte differentiation. A modified chondrocyte in which the expression or function of salt-inducible kinase 3 gene is inhibited or enhanced can be used to ameliorate a disease associated with reduced cartilage volume and/or a disease associated with impaired cartilage growth.
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