首页>
外国专利>
Methods and kits for detecting genetic polymorphisms associated with coronary events and drug response
Methods and kits for detecting genetic polymorphisms associated with coronary events and drug response
展开▼
机译:用于检测与冠脉事件和药物反应相关的遗传多态性的方法和试剂盒
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides compositions and methods based on genetic polymorphisms that are associated with coronary heart disease (particularly myocardial infarction), aneurysm/dissection, and/or response to drug treatment, particularly statin treatment. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection. In particular, the polymorphism is the KIF6 Trp719Arg variant.
展开▼