TRANSDERMAL DELIVERY SYSTEM OF BIOACTIVE MOLECULES OF SKIN USING INTRACELLULAR MOLECULE DELIVERY PEPTIDES

摘要

The present invention relates to a composition for transdermal delivery containing bioactive molecules of skin in which intracellular molecule delivery peptides are fused. More particularly, the composition is one in which peptides having superior in vivo molecular delivery ability are fused to bioactive molecules of skin which may not be easily permeated into the stratum corneum of skin due to molecular size and physical properties. The composition may exhibit excellent in vitro and in vivo skin permeability, and therefore, can be valuably used in delivering compounds having various advantages into skin cells and formulated into various forms. Thus, the composition can be valuably used as a material for functional cosmetics.