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Process for preparing guggulsterones and guggulsterol

机译：制备古古甾酮和古古甾醇的方法

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摘要

The present invention relates to a method for selective preparing 4,17 (20)-E-pregnadiene-3,16-dione (E-guggulsterone) of the formula (III) and 4,17 (20)-Z-pregnadiene-3,16-dione (Z-guggulsterone) of the formula (IV) having an effect of lowering the elevated low density lipoprotein (LDL) and high levels of the cholesterol effectively, and elevating the low levels of the high density lipoprotein (HDL) from a easy-available steroid of the following formula (I).;Also, the present invention provides a method for preparation of the compound of the above formula (II).

机译：本发明涉及一种选择性地制备式（III）的4，17（20）- E -孕二烯-3,16-二酮（ E -guggulsterone）的方法）和式（IV）的4,17（20）- Z -孕二烯-3,16-二酮（Z-古古甾酮）具有降低升高的低密度脂蛋白（LDL）和高水平的胆固醇有效地降低了下式（I）的类固醇从高水平的高密度脂蛋白（HDL）的水平。;此外，本发明提供了制备高水平的胆固醇的方法上式（II）。 展开▼

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公开/公告号EP2594577A1

专利类型

公开/公告日2013-05-22

原文格式PDF

申请/专利权人 SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION;
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申请/专利号EP20130153819

发明设计人 KANG HEONJOONG;HAM JUNGYEOB;CHIN JUNGWOOK;
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申请日2004-04-24

分类号C07J13/00;C07J1/00;C07J21/00;C07J33/00;C07J51/00;C07J71/00;

国家 EP

入库时间 2022-08-21 16:29:39

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