首页> 外国专利> Pharmacological composition containing a C12orf59 protein or a polynucleotide encoding C12orf59 for the prevention and treatment of cancer

Pharmacological composition containing a C12orf59 protein or a polynucleotide encoding C12orf59 for the prevention and treatment of cancer

机译:包含C12orf59蛋白或编码C12orf59的多核苷酸的药物组合物,用于预防和治疗癌症

摘要

As explained hereinbefore, the C12orf59 gene of the present invention suppresses cancer cell invasion and inhibits cancer cell survivability, and the over-expression of C12orf59 protein or a fragment thereof inhibits cancer cell invasion, so that C12orf59 gene or a fragment thereof not only can be effectively used for the pharmaceutical composition for preventing and treating cancer but also can be used as a clinical marker for screening a cancer treatment agent candidate, for diagnosing various cancers or for predicting pathological stage. In addition, the C12orf59 gene or a fragment thereof of the present invention can be used for the method for preventing and treating cancer and for the preparation of a pharmaceutical composition for preventing and treating cancer.
机译:如前所述,本发明的C12orf59基因抑制癌细胞的侵袭并抑制癌细胞的存活性,并且C12orf59蛋白或其片段的过表达抑制癌细胞的侵袭,因此C12orf59基因或其片段不仅可以有效地用于预防和治疗癌症的药物组合物,还可用作筛选癌症治疗剂候选物,诊断各种癌症或预测病理分期的临床标志物。另外,本发明的C12orf59基因或其片段可以用于预防和治疗癌症的方法以及用于制备用于预防和治疗癌症的药物组合物。

著录项

  • 公开/公告号KR101198714B1

    专利类型

  • 公开/公告日2012-11-12

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20110089601

  • 发明设计人 김세미;이윤희;

    申请日2011-09-05

  • 分类号A61K38/16;A61K38/17;A61K39/21;A61P35;

  • 国家 KR

  • 入库时间 2022-08-21 16:28:14

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