PROBE FOR DETECTING POLYMORPHISM OF PIK3CA GENE WITH HIGH SENSITIVITY, A METHOD FOR DETECTING POLYMORPHISM, A METHOD FOR DETERMINING DRUG EFFICACY, AND A REAGENT KIT FOR DETECTING POLYMORPHISM

摘要

PURPOSE: A probe for detecting polymorphism, a method for detecting polymorphism, a method for determining drug efficacy, and a reagent kit for detecting polymorphism are provided to simply detect PIK3CA gene polymorphism.;CONSTITUTION: An oligonucleotide is hybridizable with a complementary strand of a sequence which is complementary to 5-50 base sequences containing 151th-155th bases in sequence number 4 or 5. The base corresponding to 151th base is cytosine which is labeled with a fluorescence pigment.;COPYRIGHT KIPO 2013;[Reference numerals] (AA) Detection signal; (BB,DD) Temperature[°C]; (CC) Differential value of the detection signal;