COMPOSITION CONTAINING SODIUM BUTYRATE AS AN ACTIVE INGREDIENT FOR SUPPRESSING HIGH GLUCOSE-INDUCED INFLAMMATION

摘要

PURPOSE: A composition for suppressing high glucose-induced inflammation is provided to suppress secretion of inflammatory cytokines such as TNF-alpha and IL-6, thereby preventing and treating inflammation caused by high glucose.;CONSTITUTION: A pharmaceutical composition for suppressing high glucose-induced inflammation contains sodium butyrate as an active ingredient. Sodium butyrate is denoted by chemical formula 1. The pharmaceutical composition suppresses generation of inflammatory cytokines induced by high glucose. The inflammatory cytokines are tumor necrosis factor-alpha (TNF-alpha) or interleukin-6 (IL-6). A pharmaceutical composition for preventing and treating high glucose-induced inflammatory diseases contains sodium butyrate as an active ingredient.;COPYRIGHT KIPO 2013