Quantitation methods using high-mass y-type signal ions for proteins and peptides labeled with isobaric tags

摘要

The present invention is a method of analyzing the amount of each analyte quantification of different proteins and peptides using a labeling claim and to provide , after combining a labeling agent to the analyte fall away only a portion of the labeling agent with the remaining tandem mass analysis , utilizing y- type fragment ions of a large mass including a new body to perform a quantitative analysis is provided a method . ;