Cell line which is transfected with Wnt active measurement vector and High-Throughput Screening method of selective ligands by using it

摘要

the present invention for measuring the activity of Wnt is transformed with a recombinant vector using this cell line and the efficiency of the screening method relates , more particularly, to a search method of a recombinant vector , transformed cell lines and the related materials and using the same active Wnt protein with the vector for Wnt activity measurement , transgenic cell line containing the recombinant vector of the present invention and it is Wnt protein by efficiently navigate the substance associated with the activity could be used effectively in the development of osteoporosis therapies , supplements osteoporosis and bone metabolic diseases . ;