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Transformed Cell Lines Expressing Human Melanopsin and Methods for Screening Circadian Rhythm-Related Biomolecules Using the Same
Transformed Cell Lines Expressing Human Melanopsin and Methods for Screening Circadian Rhythm-Related Biomolecules Using the Same
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机译:表达人类黑素蛋白的转化细胞系及使用其筛选昼夜节律相关生物分子的方法
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摘要
PURPOSE: A transformed cell line which expresses human melanopsin and a method for screening a material which affects circadian rhythm-related biomolecules and circadian rhythm is provided to early diagnose various diseases. CONSTITUTION: A transformed animal cell line which expresses human melanopsin is prepared by transforming an animal cell with a vector containing a nucleotide sequence of sequence number 1, which encodes human melanopsin proteins. A method for screening circadian rhythm-related biomolecules comprises: a step of transforming an animal cell line with the vector and preparing the transformed animal cell line; a step of activating the melanopsin proteins in the transformed animal cell line; and a step of analyzing the expression of a circadian rhythm gene in the transformed animal cells.
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