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COMBINATION DRUG CONTAINING PROBUCOL AND A TETRAZOLYLALKOXY-DIHYDROCARBOSTYRIL DERIVATIVE WITH SUPEROXIDE SUPRESSANT EFFECTS
COMBINATION DRUG CONTAINING PROBUCOL AND A TETRAZOLYLALKOXY-DIHYDROCARBOSTYRIL DERIVATIVE WITH SUPEROXIDE SUPRESSANT EFFECTS
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机译:含普鲁布罗的药物与四唑基环氧-二羰基碳氢化合物衍生物的过氧化物抑制剂作用
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摘要
This invention relates to a combination drug comprising a combination of a tetrazolylalkoxy-dihydrocarbostyril derivative of the formula: wherein R is cycloalkyl, A is lower alkylene, and the bond between 3-and 4-positions of carbostyril nucleus is single bond or double bond, or a salt thereof and Probucol, which is useful for preventing and treating cerebral infarction including acute cerebral infarction and chronic cerebral infarction, arteriosclerosis, renal diseases (e.g. diabetic nephropathy, renal failure, nephritis), and diabetes owing to synergistic superoxide suppressant effects of the combination.
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