APPLICATION OF 4-AMINOPYRIDINE TO IMPROVE CONDITION IN NEURO-COGNITIVE AND / OR NEUROPSYCHIATRIC DISORDERS IN PATIENTS WITH DEMILINIZING AND OTHER DISEASES OF THE NERVOUS SYSTEM

摘要

1. A method of administering a dose of aminopyridine to improve at least one neurocognitive or neuropsychiatric parameter in a patient. The method of claim 1, wherein the patient has a demyelinating state, MS, traumatic brain damage, cerebral palsy, or post-radiation encephalopathy. The method according to claim 3, where the patient has RS. 4. The method according to claim 1, where the treatment takes place for at least 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 or more than 12 weeks. The method of claim 1, wherein the aminopyridine is 4-aminopyridine. The method of claim 1, wherein the aminopyridine is Fampridine-SR.7. The method of claim 6, wherein fampridine-SR is administered at a dose of 10 mg twice daily. The method according to claim 1 in combination with another therapeutic agent aimed at a neurocognitive or neuropsychiatric disorder. The method of claim 1, wherein the patient has MS, the method comprising administering in combination with another therapeutic agent directed to MS. The method of claim 1, further comprising the step of identifying whether the patient has a neurocognitive or neuropsychiatric disorder. A method for treating a neurocognitive or neuropsychiatric disorder, comprising: determining a patient having a neurocognitive or neuropsychiatric disorder, identifying a patient who has a neurocognitive or neuropsychiatric disorder, or diagnosing a patient with a neurocognitive or neuropsychiatric disorder; and implementing an aminopyridine dosage regimen to improve at least one neurocognitive or neuropsychiatric parameter in a patient. The method according to claim 11, where the introduction stage includes the appointment of an aminopyridine dosing regimen for ul